Primary Lactose Intolerance, Hypolactasia
The most common form is primary, genetically determined lactose intolerance. It is not a disease, but a natural genetic variation in which the body gradually reduces lactase production with age. It typically begins to appear during adolescence or adulthood.
Why Genetic Testing Makes Sense
- Certainty and an end to uncertainty: the test helps verify whether your symptoms are related to a genetic predisposition.
- Clear result: you will receive a clear report explaining what your genotype means.
- Practical recommendations: the report includes recommendations on how to adjust your diet to help prevent symptoms from recurring unnecessarily.
The result of the genetic test can help you adjust your diet in a targeted way, so that you avoid unnecessary restrictions while minimising symptoms.
What Exactly Does the Test Examine?
The Lacto DNA Test uses real-time PCR to examine two known variants associated with lactase activity:
- c.-13910T/C, rs4988235
- c.-22018A/G, rs182549
These variants are located in the regulatory region of the LCT gene, the gene for the lactase enzyme, which is essential for digesting lactose.
What Type of Sample Can Be Used?
The test can be performed using:
- Blood
- A buccal swab, taken from the lining of the mouth
Important Limitation, So the Results Are Understood Correctly
This genetic test assesses predisposition to primary, inherited lactose intolerance. If symptoms are significant but primary genetic LCI is unlikely, it is advisable to consult a doctor and consider other possible causes of digestive problems, such as temporary or secondary reduction of lactase after intestinal infections.
What to Do After Receiving the Result: Treatment and Lifestyle Measures for Lactose Intolerance
In primary lactose intolerance, there is no “one tablet” treatment that can change the genetic predisposition. The good news is that, in most cases, symptoms can be managed very well through dietary adjustment and appropriate food choices.
1) You Do Not Have to Exclude All Dairy Products
Lactose intolerance does not automatically mean a complete ban on dairy products. Many people tolerate small amounts of lactose, especially:
- When they are spread throughout the day
- When they are consumed as part of a meal, not on an empty stomach
- When they are products naturally low in lactose
2) Choose More Suitable Dairy Products
The following are often better tolerated:
- Hard and mature cheeses, which usually contain very little lactose
- Fermented products, such as some yoghurts or kefirs, where part of the lactose has been broken down
- Lactose-free options, such as milk, yoghurt, curd and similar products
3) Lactase Enzyme May Help
In situations where you want to consume a dairy product, for example in a restaurant or while travelling, a lactase enzyme supplement may be used. In many people, it significantly reduces symptoms, although the effect is individual.
4) Watch Out for Hidden Lactose
Lactose may also be present in foods where you might not expect it, such as some baked goods, processed meats or instant products. It helps to:
- Read ingredient lists
- Look for terms such as lactose, milk powder or whey
5) Think About Calcium and Vitamin D
If you significantly reduce dairy products, it is important to monitor:
- Calcium intake, with alternative sources such as some calcium-rich mineral waters, fish with bones, leafy greens and fortified plant-based drinks
- Vitamin D, especially in winter
- Possible supplementation, ideally discussed with a doctor or nutritional therapist
6) When to Pay Attention and Consult a Doctor
If symptoms are severe, long term or accompanied by:
- Weight loss, blood in the stool or night-time diarrhoea
- Anaemia or significant fatigue
- Symptoms even without consuming dairy products
Further examination is advisable. Not all digestive problems are related to lactose. Sometimes they may be caused by secondary intolerance, intestinal inflammation or other conditions.
Coverage and Booking
In justified cases, the Lacto DNA Test may be prescribed by a doctor and the test may then be covered by health insurance. The test can also be taken as a self-paid examination. For pricing and booking, please contact our centre.
