MFSS: Innovative and Gentle Selection of the Best Sperm
The quality of a sperm cell is just as important for the creation of a healthy embryo as the quality of an egg. Microfluidic Sperm Sorting (MFSS) is an advanced laboratory method that allows us to select the highest-quality, fastest and genetically healthiest sperm for fertilisation in a natural and gentle way.
What is MFSS and how does it mimic nature?
MFSS uses a special single-use chip whose internal structure of microchannels mimics the natural environment of the female reproductive system (specifically the fallopian tubes). The sperm sample is applied to the inlet and only the most capable sperm are able to actively swim through the micro-barriers to the "target" chamber, where they are then collected. This process effectively separates healthy, motile sperm from slow, damaged or dying ones.
Key advantages of the MFSS method:
- Increased cycle success rate by up to 35%: Studies demonstrate that the use of sperm selected by MFSS increases the proportion of genetically healthy (euploid) embryos and the overall success rate of treatment.
- Better sperm quality: The result is sperm with demonstrably better morphology, higher genetic quality (lower DNA fragmentation) and more than double the viability and motility.
- Maximum gentleness: Unlike standard processing methods (such as centrifugation), MFSS requires no prior sample preparation and does not expose sperm to oxidative stress that can damage them.
When Do We Recommend the MFSS Method?
This method is suitable for a wide range of couples, but offers the greatest benefit in the following cases:
- Repeatedly unsuccessful intrauterine insemination (IUI).
- Low fertilisation rate of eggs by ICSI in a previous cycle.
- Recurrent miscarriages in the patient's history.
- Repeated unsuccessful embryo transfers (implantation failure).
- Poor embryo quality in previous IVF cycles.
- Detected elevated DNA fragmentation of sperm.
Frequently Asked Questions (FAQs)
Do you want to use the best available technologies for your treatment? Ask our specialists at Gennet about the MFSS method.
Can MFSS be combined with ICSI?
Yes, it is the ideal combination. The MFSS method selects the best sperm, which are then used for fertilisation by ICSI, maximising the chance of creating a high-quality embryo.
Does MFSS replace other andrological tests?
No. MFSS is a method for processing and selecting sperm for fertilisation. It does not replace diagnostic tests such as a spermogram or a DNA fragmentation test; on the contrary, it builds on their results.
Is the MFSS method financially demanding?
MFSS is a premium laboratory method that is charged separately. However, compared to its potential benefit (increased success rate and reduced number of cycles needed), it represents a very cost-effective investment in your treatment.
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