MESA and TESE: Surgical Sperm Retrieval Techniques

Surgical sperm retrieval offers a modern solution for men who have no sperm—or at least no viable sperm—in their ejaculate. Advanced microsurgical techniques such as MESA (Microsurgical Epididymal Sperm Aspiration) and TESE (Testicular Sperm Extraction) allow sperm to be collected directly from the epididymis or testicular tissue for use in ICSI fertilisation.

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What Are MESA and TESE and How Do They Work?

Both procedures are performed on an outpatient basis under local or general anaesthesia.

Samples are analysed immediately, and if viable sperm are found, they are prepared for egg fertilisation.

MESA

A microsurgical technique in which sperm are aspirated from the epididymis using a fine needle. This method is minimally invasive and highly effective in cases of obstructive azoospermia.

TESE

Sperm are extracted directly from the testicular tissue. This method is primarily used for non-obstructive azoospermia, where sperm production in the ejaculate is absent or severely impaired.

Key Benefits of MESA / TESE:

  • Fertility option for severe male infertility – enables fertilisation even in cases of complete absence of sperm in the ejaculate (azoospermia).
  • High success rates – up to 95% in obstructive and up to 50% in non-obstructive azoospermia.
  • Safe and efficient – the procedure is short, and most patients experience minimal downtime. 
  • Compatible with ICSI – even a very small number of retrieved sperm can be used with ICSI successfully.

When Do We Recommend Surgical Sperm Retrieval?

These techniques are recommended in the following situations:

  • Azoospermia – complete absence of sperm in the ejaculate.
  • Necrozoospermia – only non-viable (dead) sperm are present.
  • Failed ejaculation – due to erectile dysfunction or retrograde ejaculation.
  • Post-vasectomy – sperm cannot be retrieved by natural means.
  • Genetic or hormonal causes – when the sperm production is limited to testicular tissue only.

Frequently Asked Questions (FAQs)

Do you have more questions about MESA or TESE? Ask our specialists at Gennet.

Is the procedure painful?
  • Surgical sperm retrieval
  • Special laboratory methods

No, the procedure is performed under local or general anaesthesia. Most patients report minimal discomfort. Mild soreness may occur afterwards.

Are sperm retrieved via MESA/TESE ready for immediate use?
  • Surgical sperm retrieval
  • Special laboratory methods

Yes, if viable sperm are found, they are either used right away for ICSI fertilisation or cryopreserved for future treatment.

How long is the recovery time?
  • Surgical sperm retrieval
  • Special laboratory methods

We recommend rest for 1–3 days following the procedure. Most patients return to normal activities within a few days.

How much does it cost?
  • Surgical sperm retrieval

The cost depends on the type of procedure (MESA or TESE), the type of anaesthesia used, and the complexity of the retrieval. Your doctor will provide a detailed quote during your consultation, or you can find pricing in our fee schedule.

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