In vitro fertilization (IVF)
This treatment method became the most efficient procedure of assisted reproduction in the course of thirty years in which this method of assisted reproduction has been known. IVF is suitable for women with blocked fallopian tubes or without fallopian tubes with a fertile partner.
What is the course of treatment with IVF?
Course of treatment of IVF has several stages.
1) Stimulation phase
The physician attempts to grow many pouches (follicles) on the surface of ovaries in this stage of treatment so that more eggs can be collected and the chance of conception is higher.
- the patient is given hormones for ovarian stimulation
- stimulation is continuously monitored with ultrasound and blood tests
Approximately 9 - 14 days after the start of stimulation when the leading follicle reaches the required size, the patient is given hCG injection around 36 - 40 hours before egg collection.
2) Egg collection (ovum pick up – OPU)
The procedure lasts 10 – 15 minutes in general anesthesia. A thin needle is inserted through the vagina directly to ovaries.
- preoperative evaluation must be done several days before the collection
- OPU is performed early in the morning
- you will discuss the details of collection with the anesthesiologist on duty on arrival in GENNET
- the surgeon penetrates into mature follicles during ultrasound monitoring and collects eggs with gentle suction during the intervention*
- the patient rests 1 to 2 hours under supervision in one of our comfortable rooms after the procedure
- the embryologist informs you about the result of collection before you leave
- you take medication to support corpus luteum and improve the quality of endometrium in the following days
- the eggs are transferred into a special solution after being collected from follicles
- sperm with normal motility and form is added subsequently
3) Violation of uterine lining (endometrium)
Violation of endometrium can increase its implantation ability in selected patients. The transferred embryo can therefore better adhere to uterine lining. The procedure lasts a few minutes and is performed under visual control when inserting the hysteroscope. The patient is under general anesthesia, or without anesthesia, if it is more convenient for her.
4) Embryo transfer (ET)
Embryo transfer is one of the most important parts of the entire IVF procedure. The physician transfers the embryo through the vagina in the uterus with a thin catheter in the painless intervention. It is convenient that the patient has a full bladder, since the position of the catheter is checked with ultrasound. It is possible to watch the progress of the procedure on the screen in the operating theater. The partner of the patient can be present during the entire transfer.
IVF procedure after egg collection as follows:
- the embryologist can find out approximately 16 to 18 hours after OPU whether one of the sperm cells penetrated the egg cell and fertilized it
- fertilized egg is gradually divided into 2, 4, 8 and more cells
- fertilized embryos are transferred approximately on day 3 after OPU (for extended cultivation of embryos on day 4 - 6 after OPU)
- one or several embryos are transferred during the actual transfer*
- we recommend the patients to rest half an hour or an hour in one of our rooms after the intervention
- the patient receives all necessary medication for the following days before leaving the clinic
- we recommend to rest and take sick-leave after the embryo transfer
- remaining embryos can be frozen
- pregnancy test is done approximately 14 days after the embryo transfer with a blood test or urine test
* Our center recommends to transfer only one embryo (single embryo transfer - SET) to reduce the risk of multiple pregnancy.