A new laboratory method increasing the chance of getting pregnant
The ZONA FREE method is a special type of assisted fertilisation and implantation where the embryo is completely stripped of the outer layer (Zona pellucida – ZP). The method is recommended for clients in whom antibodies against ZP – AZP proteins have been shown.
AZP is an immunopathology that contributes to fertility disorders. Before treatment with IVF, although immunologists try to suppress the production of AZP with drugs that weaken the immune response, the treatment is not always successful enough to make the antibodies completely disappear from the circulation.
Even if the blood test for AZP shows negative, its presence can never be ruled out below the detection limit, which can still harm the embryo. However, an embryo deprived of ZP protein residues is "uninteresting" to AZP, and once it is inserted into the uterus, AZP can no longer harm it.
After removal of the embryo outer layer using the ZONA FREE method, in 2019 65% of patients with proven AZP became pregnant
Who is the treatment for:
- Patients who have been shown to have ZP antibodies.
- Other cases, according to the physician's recommendation.
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Dear clients, we would like to inform you about the limited service of our clinic from 24st December 2022 to 2nd January 2023 due to Christmas holidays and validation of our laboratory devices.
The GENNET clinic is part of the Future Life group operating in numerous European countries. This allows our Irish patients to profit from an exclusive partnership with Reproscan Ireland.
Advances in the field of assisted reproduction are very fast and new methods and approaches that keep treatment rates high are emerging every day. Since we are often asked about which advanced methods of sperm selection we offer at our clinic and the differences between them, we asked the Head of IVF Laboratories - Ing. Radomír Křen, Ph.D., to introduce these methods in detail, within the historical context.
Dear clients, we are the only assisted reproduction centre in the Czech Republic that has at its disposal a revolutionary incubator with time-lapse imaging Embryoscope + equipped with IDAScore software.